Presynaptic Targeting of GFP-VAMP in a Transfected Neuron

The experiment shows the distribution of a recombinant version of a synaptic vesicle protein, i.e. GFP-tagged VAMP/Synaptobrevin (green), in a transfected neuron (left). All neurons are stained using MAP2 (magenta), to show their dendrites and soma. GFP-VAMP puncta observed in the right part of the field of view represent synaptic vesicle accumulations in the axon of the transfected neuron.

 

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Courtesy Donatus Riemann and Thomas Dresbach / UMG, CNMPB